BDBM313446 US10167270, Example 145

SMILES CC(C)(C)OC(=O)NCCCCCC(=O)Nc1ccc(cc1)-c1nc(NC2Cc3ccccc3C2)c2ccccc2n1

InChI Key InChIKey=IMWFXFHZTKSNCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313446   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM313446(US10167270, Example 145)
Affinity DataIC50:  5.60nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent