BDBM313530 N-(3-(2-aminopropan-2- yl)-5- (trifluoromethyl)phenyl)- 3-(5-(3-hydroxyoxetan- 3-yl)-6-methoxypyridin- 3-yl)-4- methylbenzamide::US10167279, Example 150

SMILES COc1ncc(cc1C1(O)COC1)-c1cc(ccc1C)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(C)(C)N

InChI Key InChIKey=SOFHDPONURJURV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313530   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM313530(N-(3-(2-aminopropan-2- yl)-5- (trifluoromethyl)phe...)
Affinity DataIC50:  3.00E+3nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent