BDBM313534 N-(3-(2-(2- hydroxyethoxy)-6-(3- methoxyoxetan-3- yl)pyridin-4-yl)-4- methylphenyl)-2- (trifluoromethyl)isonicotin- amide::US10167279, Example 157

SMILES COC1(COC1)c1cc(cc(OCCO)n1)-c1cc(NC(=O)c2ccnc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=AIHPQERPNVZGJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313534   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM313534(N-(3-(2-(2- hydroxyethoxy)-6-(3- methoxyoxetan-3- ...)
Affinity DataIC50:  300nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent