BDBM313539 N-(6'-ethoxy-2-methyl- 5'-(tetrahydro-2H-pyran- 4-yl)-[3,3'-bipyridin]-5- yl)-6-(trifluoromethyl) pyridazine-4-carboxamide::US10167279, Example 163

SMILES CCOc1ncc(cc1C1CCOCC1)-c1cc(NC(=O)c2cnnc(c2)C(F)(F)F)cnc1C

InChI Key InChIKey=XPLCJCINVSLPKA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313539   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM313539(N-(6'-ethoxy-2-methyl- 5'-(tetrahydro-2H-pyran- 4-...)
Affinity DataIC50:  300nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent