BDBM313550 N-(3-(2-((2- hydroxyethyl)amino)-6- (tetrahydro-2H-pyran-4- yl)pyridin-4-yl-4- methylphenyl)-3- (trifluoromethyl) benzamide::US10167279, Example 174

SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(NCCO)nc(c1)C1CCOCC1

InChI Key InChIKey=QQKXKFGXJFXNAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313550   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM313550(N-(3-(2-((2- hydroxyethyl)amino)-6- (tetrahydro-2H...)
Affinity DataIC50:  331nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent