BDBM31389 CHEMBL29180::terephthalamide scaffold, 36

SMILES COC(=O)CNC(=O)c1ccc(cc1)C(=O)N(C)C

InChI Key InChIKey=ZWVJLHBALJEXDG-UHFFFAOYSA-N

Data  1 KI  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31389   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM31389(CHEMBL29180 | terephthalamide scaffold, 36)
Affinity DataKi: >3.00E+4nMAssay Description:Binding affinity for Bcl-xL was assessed by a fluorescence polarizationassay using a fluorescently labeled 16-mer Bak-peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM31389(CHEMBL29180 | terephthalamide scaffold, 36)
Affinity DatapH: 7.4 T: 2°CAssay Description:Fluorescence polarization experiments were conducted on a Photon Technology International instrument using a 0.3 cm path length cuvette. Spectra were...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed