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BDBM314161 3-{[(6-chloro-1-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl)methyl]amino}pyridine-4-carboxylic acid::US10179769, Example 68::US9611221, Example 68::US9725441, Example 68::US9828343, Example 68

SMILES: OC(=O)c1ccncc1NCC1CCCc2cc(Cl)ccc12

InChI Key: InChIKey=WQNPSJUCFWEQLQ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 314161   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 5B


(Homo sapiens (Human))
BDBM314161
PNG
(3-{[(6-chloro-1-hydroxy-1,2,3,4-tetrahydronaphthal...)
Show SMILES OC(=O)c1ccncc1NCC1CCCc2cc(Cl)ccc12
Show InChI InChI=1S/C17H17ClN2O2/c18-13-4-5-14-11(8-13)2-1-3-12(14)9-20-16-10-19-7-6-15(16)17(21)22/h4-8,10,12,20H,1-3,9H2,(H,21,22)
PDB

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PC cid
PC sid
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US Patent
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research Inc

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10179769 (2019)


BindingDB Entry DOI: 10.7270/Q2J38VPZ
More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C


(Homo sapiens (Human))
BDBM314161
PNG
(3-{[(6-chloro-1-hydroxy-1,2,3,4-tetrahydronaphthal...)
Show SMILES OC(=O)c1ccncc1NCC1CCCc2cc(Cl)ccc12
Show InChI InChI=1S/C17H17ClN2O2/c18-13-4-5-14-11(8-13)2-1-3-12(14)9-20-16-10-19-7-6-15(16)17(21)22/h4-8,10,12,20H,1-3,9H2,(H,21,22)
PDB

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antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research Inc

US Patent


Assay Description
JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...


US Patent US9828343 (2017)


BindingDB Entry DOI: 10.7270/Q2ST7S40
More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C


(Homo sapiens (Human))
BDBM314161
PNG
(3-{[(6-chloro-1-hydroxy-1,2,3,4-tetrahydronaphthal...)
Show SMILES OC(=O)c1ccncc1NCC1CCCc2cc(Cl)ccc12
Show InChI InChI=1S/C17H17ClN2O2/c18-13-4-5-14-11(8-13)2-1-3-12(14)9-20-16-10-19-7-6-15(16)17(21)22/h4-8,10,12,20H,1-3,9H2,(H,21,22)
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research Inc

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9725441 (2017)


BindingDB Entry DOI: 10.7270/Q29Z971T
More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C


(Homo sapiens (Human))
BDBM314161
PNG
(3-{[(6-chloro-1-hydroxy-1,2,3,4-tetrahydronaphthal...)
Show SMILES OC(=O)c1ccncc1NCC1CCCc2cc(Cl)ccc12
Show InChI InChI=1S/C17H17ClN2O2/c18-13-4-5-14-11(8-13)2-1-3-12(14)9-20-16-10-19-7-6-15(16)17(21)22/h4-8,10,12,20H,1-3,9H2,(H,21,22)
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



Celgene Quanticel Research Inc

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9611221 (2017)


BindingDB Entry DOI: 10.7270/Q26975NT
More data for this
Ligand-Target Pair