BDBM314161 3-{[(6-chloro-1-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl)methyl]amino}pyridine-4-carboxylic acid::US10179769, Example 68::US9611221, Example 68::US9725441, Example 68::US9828343, Example 68

SMILES: OC(=O)c1ccncc1NCC1CCCc2cc(Cl)ccc12

InChI Key: InChIKey=WQNPSJUCFWEQLQ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 314161   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM314161 (3-{[(6-chloro-1-hydroxy-1,2,3,4-tetrahydronaphthal...) Show SMILES OC(=O)c1ccncc1NCC1CCCc2cc(Cl)ccc12 Show InChI InChI=1S/C17H17ClN2O2/c18-13-4-5-14-11(8-13)2-1-3-12(14)9-20-16-10-19-7-6-15(16)17(21)22/h4-8,10,12,20H,1-3,9H2,(H,21,22)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research Inc US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10179769 (2019) BindingDB Entry DOI: 10.7270/Q2J38VPZ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM314161 (3-{[(6-chloro-1-hydroxy-1,2,3,4-tetrahydronaphthal...) Show SMILES OC(=O)c1ccncc1NCC1CCCc2cc(Cl)ccc12 Show InChI InChI=1S/C17H17ClN2O2/c18-13-4-5-14-11(8-13)2-1-3-12(14)9-20-16-10-19-7-6-15(16)17(21)22/h4-8,10,12,20H,1-3,9H2,(H,21,22)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research Inc US Patent					Assay Description JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...				US Patent US9828343 (2017) BindingDB Entry DOI: 10.7270/Q2ST7S40
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM314161 (3-{[(6-chloro-1-hydroxy-1,2,3,4-tetrahydronaphthal...) Show SMILES OC(=O)c1ccncc1NCC1CCCc2cc(Cl)ccc12 Show InChI InChI=1S/C17H17ClN2O2/c18-13-4-5-14-11(8-13)2-1-3-12(14)9-20-16-10-19-7-6-15(16)17(21)22/h4-8,10,12,20H,1-3,9H2,(H,21,22)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research Inc US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US9725441 (2017) BindingDB Entry DOI: 10.7270/Q29Z971T
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM314161 (3-{[(6-chloro-1-hydroxy-1,2,3,4-tetrahydronaphthal...) Show SMILES OC(=O)c1ccncc1NCC1CCCc2cc(Cl)ccc12 Show InChI InChI=1S/C17H17ClN2O2/c18-13-4-5-14-11(8-13)2-1-3-12(14)9-20-16-10-19-7-6-15(16)17(21)22/h4-8,10,12,20H,1-3,9H2,(H,21,22)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research Inc US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US9611221 (2017) BindingDB Entry DOI: 10.7270/Q26975NT
					More data for this Ligand-Target Pair