BDBM314789 (3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((S)-1,1,1- trifluoro-2-methoxypropan-2-yl)- 5,6,7,7a-tetrahydro-3aH- pyrano[3,2-d]thiazole-6,7-diol (Faster eluting isomer by HPLC)::US9611275, Example 74

SMILES: CO[C@@](C)([C@H]1O[C@@H]2SC(=N[C@@H]2[C@@H](O)[C@@H]1O)N(C)C)C(F)(F)F

InChI Key: InChIKey=MATMWPJDCPNCOQ-GWMGTZGCSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) (Homo sapiens (Human))	BDBM314789 ((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((S)-1,1,1...) Show SMILES CO[C@@](C)([C@H]1O[C@@H]2SC(=N[C@@H]2[C@@H](O)[C@@H]1O)N(C)C)C(F)(F)F Show InChI InChI=1S/C12H19F3N2O4S/c1-11(20-4,12(13,14)15)8-7(19)6(18)5-9(21-8)22-10(16-5)17(2)3/h5-9,18-19H,1-4H3/t5-,6-,7+,8+,9-,11+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alectos Therapeutics Inc US Patent					Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...				US Patent US9611275 (2017) BindingDB Entry DOI: 10.7270/Q2833V4D
					More data for this Ligand-Target Pair