BDBM31524 5-amino-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide (I-1)::AKOS015840255::GRL0617::Naphthalene and Benzamide Derivative, 25::SARS-CoV-2 PLpro Inhibitor, GRL0617 (1)::US20240166598, Compound GRL0167::med.21724, Compound 159

SMILES: C[C@@H](NC(=O)c1cc(N)ccc1C)c1cccc2ccccc12

InChI Key: InChIKey=UVERBUNNCOKGNZ-UHFFFAOYSA-N

Data: 1 KI  23 IC50  4 Kd  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 37 hits for monomerid = 31524   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replicase polyprotein 1ab (SARS-CoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1a (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab [1541-1855] (Human SARS coronavirus (SARS-CoV))	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.76E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1a (SARS-CoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme 2 (Human)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1a (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab [1541-1855] (Human SARS coronavirus (SARS-CoV))	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.64E+3	n/a	n/a	n/a	n/a	7.5	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1a (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1a [1564-1878] (Severe acute respiratory syndrome coronavirus (SAR...)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1a [1564-1878] (Severe acute respiratory syndrome coronavirus (SAR...)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (SARS-CoV)	BDBM31524 (Naphthalene and Benzamide Derivative, 25 | 5-amino...) Show SMILES Show InChI	GoogleScholar	UniChem		600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair