BDBM315290 1-Methyl-3-{1-[5- phenyl-2-(4- trifluoromethyl-phenyl)- 1H-imidazol-4- ylmethyl]-piperidin-4- yl}-1,3-dihydro- benzoimidazol-2-one::US10172843, Example 24

SMILES Cn1c2ccccc2n(C2CCN(Cc3nc([nH]c3-c3ccccc3)-c3ccc(cc3)C(F)(F)F)CC2)c1=O

InChI Key InChIKey=UTSOLAVZBAXWJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315290   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM315290(US10172843, Example 24 | 1-Methyl-3-{1-[5- phenyl-...)
Affinity DataIC50: 985nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent