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BDBM315384 US10172856, Example 36

SMILES: Cc1cc(ccc1N(Cc1ncco1)c1ccnc(N)n1)S(F)(F)(F)(F)F

InChI Key: InChIKey=UMTJZNBNTDBOOM-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315384   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM315384
PNG
(US10172856, Example 36)
Show SMILES Cc1cc(ccc1N(Cc1ncco1)c1ccnc(N)n1)S(F)(F)(F)(F)F
Show InChI InChI=1S/C15H14F5N5OS/c1-10-8-11(27(16,17,18,19)20)2-3-12(10)25(9-14-22-6-7-26-14)13-4-5-23-15(21)24-13/h2-8H,9H2,1H3,(H2,21,23,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
15n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
Receptor binding was assessed using isolated plasma membranes from SKNMC neuroblastoma cell lines stably expressing recombinant human H4 receptor. To...


US Patent US10172856 (2019)


BindingDB Entry DOI: 10.7270/Q2BV7JQ1
More data for this
Ligand-Target Pair