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BDBM315436 US10172856, Example 88

SMILES: CC(C)N(c1ccnc(N)n1)c1ccc(Br)cc1C

InChI Key: InChIKey=GSEZCNCGQRXZGW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315436   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM315436
PNG
(US10172856, Example 88)
Show SMILES CC(C)N(c1ccnc(N)n1)c1ccc(Br)cc1C
Show InChI InChI=1S/C14H17BrN4/c1-9(2)19(13-6-7-17-14(16)18-13)12-5-4-11(15)8-10(12)3/h4-9H,1-3H3,(H2,16,17,18)
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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
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PC cid
PC sid
UniChem
US Patent
35n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
Receptor binding was assessed using isolated plasma membranes from SKNMC neuroblastoma cell lines stably expressing recombinant human H4 receptor. To...


US Patent US10172856 (2019)


BindingDB Entry DOI: 10.7270/Q2BV7JQ1
More data for this
Ligand-Target Pair