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BDBM315477 US10172858, Table 1.1::US10172858, Table 1.22

SMILES: CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12

InChI Key: InChIKey=GYLDXIAOMVERTK-UHFFFAOYSA-N

Data: 10 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 315477   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM315477
PNG
(US10172858, Table 1.1 | US10172858, Table 1.22)
Show SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12
Show InChI InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
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n/an/a<100n/an/an/an/an/an/a



INTELLIKINE LLC

US Patent


Assay Description
This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...


US Patent US10172858 (2019)


BindingDB Entry DOI: 10.7270/Q2736T01
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha


(Homo sapiens (Human))
BDBM315477
PNG
(US10172858, Table 1.1 | US10172858, Table 1.22)
Show SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12
Show InChI InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
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UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



INTELLIKINE LLC

US Patent


Assay Description
This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...


US Patent US10172858 (2019)


BindingDB Entry DOI: 10.7270/Q2736T01
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit beta


(Homo sapiens (Human))
BDBM315477
PNG
(US10172858, Table 1.1 | US10172858, Table 1.22)
Show SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12
Show InChI InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
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n/an/a<1.00E+4n/an/an/an/an/an/a



INTELLIKINE LLC

US Patent


Assay Description
This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...


US Patent US10172858 (2019)


BindingDB Entry DOI: 10.7270/Q2736T01
More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (Human))
BDBM315477
PNG
(US10172858, Table 1.1 | US10172858, Table 1.22)
Show SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12
Show InChI InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
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n/an/a<100n/an/an/an/an/an/a



INTELLIKINE LLC

US Patent


Assay Description
This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...


US Patent US10172858 (2019)


BindingDB Entry DOI: 10.7270/Q2736T01
More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform


(Homo sapiens (Human))
BDBM315477
PNG
(US10172858, Table 1.1 | US10172858, Table 1.22)
Show SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12
Show InChI InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
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n/an/a<1.00E+3n/an/an/an/an/an/a



INTELLIKINE LLC

US Patent


Assay Description
This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...


US Patent US10172858 (2019)


BindingDB Entry DOI: 10.7270/Q2736T01
More data for this
Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR


(Homo sapiens (Human))
BDBM315477
PNG
(US10172858, Table 1.1 | US10172858, Table 1.22)
Show SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12
Show InChI InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
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n/an/a<100n/an/an/an/an/an/a



INTELLIKINE LLC

US Patent


Assay Description
This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...


US Patent US10172858 (2019)


BindingDB Entry DOI: 10.7270/Q2736T01
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha


(Homo sapiens (Human))
BDBM315477
PNG
(US10172858, Table 1.1 | US10172858, Table 1.22)
Show SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12
Show InChI InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
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UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



INTELLIKINE LLC

US Patent


Assay Description
This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...


US Patent US10172858 (2019)


BindingDB Entry DOI: 10.7270/Q2736T01
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit beta


(Homo sapiens (Human))
BDBM315477
PNG
(US10172858, Table 1.1 | US10172858, Table 1.22)
Show SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12
Show InChI InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
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n/an/a<1.00E+4n/an/an/an/an/an/a



INTELLIKINE LLC

US Patent


Assay Description
This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...


US Patent US10172858 (2019)


BindingDB Entry DOI: 10.7270/Q2736T01
More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (Human))
BDBM315477
PNG
(US10172858, Table 1.1 | US10172858, Table 1.22)
Show SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12
Show InChI InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
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n/an/a<1.00E+3n/an/an/an/an/an/a



INTELLIKINE LLC

US Patent


Assay Description
This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...


US Patent US10172858 (2019)


BindingDB Entry DOI: 10.7270/Q2736T01
More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform


(Homo sapiens (Human))
BDBM315477
PNG
(US10172858, Table 1.1 | US10172858, Table 1.22)
Show SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12
Show InChI InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
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n/an/a<1.00E+3n/an/an/an/an/an/a



INTELLIKINE LLC

US Patent


Assay Description
This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...


US Patent US10172858 (2019)


BindingDB Entry DOI: 10.7270/Q2736T01
More data for this
Ligand-Target Pair