BDBM315477 US10172858, Table 1.1::US10172858, Table 1.22

SMILES: CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12

InChI Key: InChIKey=GYLDXIAOMVERTK-UHFFFAOYSA-N

Data: 3 KI  21 IC50  6 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 315477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Target of rapamycin complex subunit LST8 (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Target of rapamycin complex subunit LST8 (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Target of rapamycin complex 2 subunit MAPKAP1 (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Target of rapamycin complex subunit LST8 (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0920	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit beta (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit beta (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM315477 (US10172858, Table 1.22 | US10172858, Table 1.1) Show SMILES Show InChI	GoogleScholar	UniChem		28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair