BDBM315516 US10172858, Table 2.12::US9828378, # 12

SMILES Nc1ncnc2n(nc(-c3cc4cc(O)ccc4[nH]3)c12)C1CCCC1

InChI Key InChIKey=HDOJSRPKBQDXJH-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 315516   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Intellikine

US Patent
LigandPNGBDBM315516(US10172858, Table 2.12 | US9828378, # 12)
Affinity DataIC50: <10nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Intellikine

US Patent
LigandPNGBDBM315516(US10172858, Table 2.12 | US9828378, # 12)
Affinity DataIC50: >500nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Intellikine

US Patent
LigandPNGBDBM315516(US10172858, Table 2.12 | US9828378, # 12)
Affinity DataIC50: >500nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM315516(US10172858, Table 2.12 | US9828378, # 12)
Affinity DataIC50: <500nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM315516(US10172858, Table 2.12 | US9828378, # 12)
Affinity DataIC50: >500nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytosolic arginine sensor for mTORC1 subunit 1(Homo sapiens (Human))
Intellikine

US Patent
LigandPNGBDBM315516(US10172858, Table 2.12 | US9828378, # 12)
Affinity DataIC50: <10nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM315516(US10172858, Table 2.12 | US9828378, # 12)
Affinity DataIC50: >500nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM315516(US10172858, Table 2.12 | US9828378, # 12)
Affinity DataIC50: >500nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM315516(US10172858, Table 2.12 | US9828378, # 12)
Affinity DataIC50: <500nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110δ/p85α from Upstate, and p110γ from Sigma) or...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM315516(US10172858, Table 2.12 | US9828378, # 12)
Affinity DataIC50: >500nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent