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BDBM31562 oxadiazole derivative, 20b

SMILES: Fc1cccc(CSc2nnc(o2)-c2ccc3OCCc3c2)c1

InChI Key: InChIKey=MUJNCQIINOKYHF-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31562   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM31562
PNG
(oxadiazole derivative, 20b)
Show SMILES Fc1cccc(CSc2nnc(o2)-c2ccc3OCCc3c2)c1
Show InChI InChI=1S/C17H13FN2O2S/c18-14-3-1-2-11(8-14)10-23-17-20-19-16(22-17)13-4-5-15-12(9-13)6-7-21-15/h1-5,8-9H,6-7,10H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 54n/an/an/an/a7.537



Takeda Pharmaceutical Co., Ltd



Assay Description
Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...


Bioorg Med Chem 17: 2017-29 (2009)


Article DOI: 10.1016/j.bmc.2009.01.019
BindingDB Entry DOI: 10.7270/Q2DR2STZ
More data for this
Ligand-Target Pair