BDBM316094 US9616064, Compound 27c

SMILES Nc1nccc(n1)-n1ccc2cc(NC(=O)CCc3ccccc3)ccc12

InChI Key InChIKey=JVEMVINZFPYWPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316094   

TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM316094(US9616064, Compound 27c)
Affinity DataIC50: 8.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM316094(US9616064, Compound 27c)
Affinity DataIC50: 5.41E+4nMAssay Description:The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent