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BDBM317597 US9624199, 7::[3-(Cyclopropylmethoxy)-1,4′-bipiperidin-1′-yl][6-(morpholin-4-yl)pyridin-3-yl]methanone

SMILES: O=C(N1CCC(CC1)N1CCCC(C1)OCC1CC1)c1ccc(nc1)N1CCOCC1

InChI Key: InChIKey=XJKLOLWFUFLUBZ-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317597   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM317597
PNG
(US9624199, 7 | [3-(Cyclopropylmethoxy)-1,4′-...)
Show SMILES O=C(N1CCC(CC1)N1CCCC(C1)OCC1CC1)c1ccc(nc1)N1CCOCC1
Show InChI InChI=1S/C24H36N4O3/c29-24(20-5-6-23(25-16-20)26-12-14-30-15-13-26)27-10-7-21(8-11-27)28-9-1-2-22(17-28)31-18-19-3-4-19/h5-6,16,19,21-22H,1-4,7-15,17-18H2
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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/an/an/a



Bayer Pharma Aktiengesellschaft

US Patent


Assay Description
To prepare cell membranes with human α1- and α2-adrenergic receptors, CHO cells stably overexpressing α1- and α2-adrenergic recep...


US Patent US9624199 (2017)

More data for this
Ligand-Target Pair