BDBM31768 CHEMBL295698::Ketoconazole::Nizoral::Panfungol

SMILES: CC(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1

InChI Key: InChIKey=XMAYWYJOQHXEEK-UHFFFAOYSA-N

Data: 15 KI  133 IC50  6 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 154 hits for monomerid = 31768   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heme oxygenase 1 (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	37
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Heme oxygenase 2 (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	7.4	37
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UDP-glucuronosyltransferase 1A1 (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 1A4 (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 1-6 (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 2B7 (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 2B10 (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Lanosterol 14-alpha demethylase (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	119	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 11B1, mitochondrial (Bovine)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	608	n/a	n/a	n/a	n/a	n/a	n/a
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Cholesterol side-chain cleavage enzyme, mitochondrial (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aromatase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 11B1, mitochondrial (Bovine)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
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Steroid 21-hydroxylase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C11 (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C11 (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cholesterol side-chain cleavage enzyme, mitochondrial (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	786	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2A2 (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	369	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 7A1 (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 2A2 (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	543	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lanosterol 14-alpha demethylase (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Steroid 21-hydroxylase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 7A1 (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
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Phospholipase A2, major isoenzyme (Pig)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1/2 (Bovine)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Steroid 17-alpha-hydroxylase/17,20 lyase (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Gonadotropin-releasing hormone receptor (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	375	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	811	n/a	n/a	n/a	n/a	n/a
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Gonadotropin-releasing hormone receptor (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	221	n/a	n/a	n/a	n/a	n/a
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Gonadotropin-releasing hormone receptor (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rat)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM31768 (Nizoral | CHEMBL295698 | Panfungol | Ketoconazole) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair