BDBM31837 2,4-Bisanilinopyrimidine, 10::Aurora Inhibitor, 35

SMILES: CCN1CCN(CC1)C(=O)Cc1ccc(Nc2ncc(F)c(Nc3ccc(cc3)C(=O)Nc3ccccc3Cl)n2)cc1

InChI Key: InChIKey=AKSIZPIFQAYJGF-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 31837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Human)	BDBM31837 (Aurora Inhibitor, 35 | 2,4-Bisanilinopyrimidine, 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	7.5	22
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					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM31837 (Aurora Inhibitor, 35 | 2,4-Bisanilinopyrimidine, 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	7.5	22
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					More data for this Ligand-Target Pair
Aurora kinase C (Human)	BDBM31837 (Aurora Inhibitor, 35 | 2,4-Bisanilinopyrimidine, 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	432	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM31837 (Aurora Inhibitor, 35 | 2,4-Bisanilinopyrimidine, 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM31837 (Aurora Inhibitor, 35 | 2,4-Bisanilinopyrimidine, 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM31837 (Aurora Inhibitor, 35 | 2,4-Bisanilinopyrimidine, 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM31837 (Aurora Inhibitor, 35 | 2,4-Bisanilinopyrimidine, 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair