BDBM319547 N-[(cyclopropyl- carbamoyl) methyl]-2-(6- fluoro-5-phenyl- 1,3-benzothiazol- 2-yl)-2-(2- methoxyethane- sulfonyl)acetamide::US10173991, Example 612

SMILES COCCS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2cc(c(F)cc2s1)-c1ccccc1

InChI Key InChIKey=SKYDAEZIHNHGBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319547   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM319547(N-[(cyclopropyl- carbamoyl) methyl]-2-(6- fluoro-5...)
Affinity DataIC50: 3nMAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent