BDBM319844 3-(5-Methyl-1,3-thiazol-2-yl)-5-[(3R)-tetrahydrofuran-3-yloxy]-N-{(1R)-1-[2-(trifluoromethyl)pyrimidin-5-yl]ethyl}benzamide::US10174016, Example 11::US10202369, Example 11::US10472354, Example 291

SMILES: C[C@@H](NC(=O)c1cc(O[C@@H]2CCOC2)cc(c1)-c1ncc(C)s1)c1cnc(nc1)C(F)(F)F

InChI Key: InChIKey=GTQPEQGDLVSFJO-UHFFFAOYSA-N

Data: 21 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 319844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2C8 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 3 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 3 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 3 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	241	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 2/3 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 3 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
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P2X purinoceptor 2/3 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 2/3 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
P2X purinoceptor 2 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 2 (Human)	BDBM319844 (US10174016, Example 11 | 3-(5-Methyl-1,3-thiazol-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair