BDBM32020 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol::4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol::4-[4-[3,4-bis(oxidanyl)phenyl]-2,3-dimethyl-butyl]benzene-1,2-diol::BDBM166684::CHEMBL52::LOX inhibitor, N/A::MLS000069451::NORDIHYDROGUAIARETIC ACID::Nordihydroguaiaretic acid (NDGA)::SMR000059049::US10857082, Compound 2.18::cid_4534

SMILES: CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1

InChI Key: InChIKey=HCZKYJDFEPMADG-UHFFFAOYSA-N

Data: 1 KI  55 IC50  9 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 65 hits for monomerid = 32020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lipoxygenase (Soybean)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid lipoxygenase ALOX15 (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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Seed linoleate 13S-lipoxygenase-1 (Soybean)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-synuclein (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-synuclein (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15B (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Transient receptor potential cation channel subfamily A member 1 (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.55E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-lipoxygenase (Bovine)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-lipoxygenase (Bovine)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Polyunsaturated fatty acid lipoxygenase ALOX12 (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Prostaglandin G/H synthase 1 (Bovine)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Seed linoleate 9S-lipoxygenase (Soybean)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lipoxygenase (Soybean)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Transthyretin (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Transthyretin (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lipoxygenase (Soybean)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lipoxygenase (Soybean)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Arachidonate 15-lipoxygenase (Pseudomonas aeruginosa)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	7.0	25
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Gag-Pol polyprotein (HIV-1)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	664	n/a	n/a	n/a	n/a	8.0	23
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14-3-3 protein gamma (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Heat shock protein HSP 90-alpha (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA-directed RNA polymerase subunit beta (Escherichia coli)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.76E+3	n/a	n/a	n/a	n/a
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POsterior Segregation (Caenorhabditis elegans)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.61E+4	n/a	n/a	n/a	n/a
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Large T antigen (SV40)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Heat shock factor protein 1 (Mouse)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a
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Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate 1-dehydrogenase (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Lipoxygenase (Soybean)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.23E+3	n/a	n/a	n/a	n/a	7.0	25
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Caspase-1 (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	25
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Heat shock protein HSP 90-alpha (Human)	BDBM32020 (LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.62E+3	n/a	n/a	n/a	n/a	7.4	23
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