BDBM32021 4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracene-2-carboxylic acid::4,5-dihydroxy-9,10-diketo-anthracene-2-carboxylic acid::4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid::4,5-dihydroxy-9,10-dioxoanthracene-2-carboxylic acid::MLS000069639::RHEIN::SMR000058210::US20230364057, Compound 82::US9238626, Rhein::cid_10168

SMILES: c1cc2c(c(c1)O)C(=O)c3c(cc(cc3O)C(=O)O)C2=O

InChI Key: InChIKey=FCDLCPWAQCPTKC-UHFFFAOYSA-N

Data: 26 IC50  1 Kd  2 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 32021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transthyretin (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Thioredoxin reductase 2, mitochondrial (Rat)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.23E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Thioredoxin reductase 1, cytoplasmic (Rat)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sialidase-2 (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RNA demethylase ALKBH5 (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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DNA oxidative demethylase ALKBH2 (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-ketoglutarate-dependent dioxygenase AlkB (Escherichia coli (strain K12))	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RNA demethylase ALKBH5 (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Heat shock protein HSP 90-alpha (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.34E+3	n/a	n/a	n/a	n/a	7.4	23
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Tissue alpha-L-fucosidase (Bovine)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA gyrase inhibitor (Escherichia coli (strain K12))	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
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DNA gyrase inhibitor (Escherichia coli (strain K12))	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	8.0	25
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Acetylcholinesterase (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	25
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Acetylcholinesterase (Electric eel)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	637	n/a	n/a	n/a	n/a	8.0	25
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Cyclin-dependent kinase 2 (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.60E+3	n/a	n/a	n/a	7.5	30
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Mitochondrial peptide methionine sulfoxide reductase (Bovine)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.55E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Plectin (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.56E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Plectin (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 7 (Human)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
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POsterior Segregation (Caenorhabditis elegans)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.92E+4	n/a	n/a	n/a	n/a
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Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM32021 (RHEIN | cid_10168 | SMR000058210 | MLS000069639 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.16E+4	n/a	n/a	n/a	n/a
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