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BDBM320275 4-(3-(4-(1H-imidazo[4,5-b]pyridin-5-yl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one::US10174023, Compound (13)

SMILES: O=C(N1CCN(CC1)c1ccc2[nH]cnc2n1)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1

InChI Key: InChIKey=HAYIEJIXTISZON-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 320275   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (human))
BDBM320275
PNG
(4-(3-(4-(1H-imidazo[4,5-b]pyridin-5-yl)piperazine-...)
Show SMILES O=C(N1CCN(CC1)c1ccc2[nH]cnc2n1)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1
Show InChI InChI=1S/C26H23N7O2/c34-25-20-7-2-1-6-19(20)22(30-31-25)15-17-4-3-5-18(14-17)26(35)33-12-10-32(11-13-33)23-9-8-21-24(29-23)28-16-27-21/h1-9,14,16H,10-13,15H2,(H,31,34)(H,27,28,29)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO., LTD

US Patent


Assay Description
HT Universal Chemiluminescent PARP Assay Kit with Histone-coated Strip Wells, commercially available from Trevigen (US), Catalog #: 4676-096-K.


US Patent US10174023 (2019)

More data for this
Ligand-Target Pair