BDBM32061 1,8-bis(azanyl)-3,6-dipyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile::1,8-diamino-3,6-bis(1-pyrrolidinyl)-2,7-naphthyridine-4-carbonitrile::1,8-diamino-3,6-dipyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile::1,8-diamino-3,6-dipyrrolidino-2,7-naphthyridine-4-carbonitrile::MLS000054131::SMR000061605::cid_2997948

SMILES: Nc1nc(cc2c(C#N)c(nc(N)c12)N1CCCC1)N1CCCC1

InChI Key: InChIKey=SSWVPYMSHHEYAB-UHFFFAOYSA-N

Data: 33 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 32061   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein RecA (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	109	n/a	n/a	n/a	n/a
TBA									Citation and Details
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M-phase inducer phosphatase 2 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Heat shock protein HSP 90-alpha (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cathepsin B (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	451	n/a	n/a	n/a	n/a	n/a	n/a
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Procathepsin L (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein phosphatase 6 (Rat)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 7 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein RecA (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	243	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein phosphatase non-receptor type 22 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 7 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cysteine protease ATG4B (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Phospholipase A2 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Apoptotic protease-activating factor 1 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptotic protease-activating factor 1 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-9 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	136	n/a	n/a	n/a	n/a	7.0	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.17E+3	n/a	n/a	n/a	n/a	6.8	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Rat)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Rat)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Rat)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Heat shock protein HSP 90-alpha (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.41E+3	n/a	n/a	n/a	n/a	7.4	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Rat)	BDBM32061 (SMR000061605 | cid_2997948 | 1,8-diamino-3,6-dipyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair