BDBM321290 N-(1-(2-chloroacetyl)piperidin-4-yl)-5- cyclopropylisoxazole-3-carboxamide::US10179773, Compound 4::US10669243, Compound 4

SMILES: c1c(onc1C(=O)NC2CCN(CC2)C(=O)CCl)C3CC3

InChI Key: InChIKey=OENTXAYVUCLRJQ-UHFFFAOYSA-N

Data: 1 KI  3 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 321290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM321290 (N-(1-(2-chloroacetyl)piperidin-4-yl)-5- cyclopropy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM321290 (N-(1-(2-chloroacetyl)piperidin-4-yl)-5- cyclopropy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM321290 (N-(1-(2-chloroacetyl)piperidin-4-yl)-5- cyclopropy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM321290 (N-(1-(2-chloroacetyl)piperidin-4-yl)-5- cyclopropy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SMYD3 (Human)	BDBM321290 (N-(1-(2-chloroacetyl)piperidin-4-yl)-5- cyclopropy...) Show SMILES Show InChI	GoogleScholar	UniChem		6.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair