BDBM321448 3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,N-dimethyl-benzamide::US10183009, Example 8

SMILES: CN(C)C(=O)c1cccc(c1)C2=CN(C(=O)c3c2cc[nH]3)CCC=C

InChI Key: InChIKey=VNCNIMOILJQAGJ-UHFFFAOYSA-N

Data: 24 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 321448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peregrin (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peregrin (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 [424-538] (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
CREB-binding protein (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
CREB-binding protein (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
CREB-binding protein (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM321448 (3-(6-but-3-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair