BDBM321740 US10183021, Compound I-529

SMILES CN(CC(O)(C(F)(F)F)C(F)(F)F)c1nc(ncc1F)-c1cc(-c2ccon2)n(Cc2ccccc2F)n1

InChI Key InChIKey=KERAZKKYGNSXPK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321740   

TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Ironwood Pharmaceuticals

US Patent
LigandPNGBDBM321740(US10183021, Compound I-529)
Affinity DataEC50: >1.00E+3nMAssay Description:Human embryonic kidney cells (HEK293), endogenously expressing soluble guanylate cyclase (sGC), were used to evaluate the activity of test compounds....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent