BDBM321751 US10183021, Compound I-491
SMILES Fc1ccc(CS(=O)(=O)Nc2ccnc(n2)-c2cc(-c3ccon3)n(Cc3ccccc3F)n2)cc1
InChI Key InChIKey=RZRDFQOTMKXFEQ-UHFFFAOYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 321751
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Ironwood Pharmaceuticals
US Patent
Ironwood Pharmaceuticals
US Patent
Affinity DataEC50: 550nMAssay Description:Human embryonic kidney cells (HEK293), endogenously expressing soluble guanylate cyclase (sGC), were used to evaluate the activity of test compounds....More data for this Ligand-Target Pair