BDBM32212 1H-indol-5-ol::cid_16054

SMILES Oc1ccc2[nH]ccc2c1

InChI Key InChIKey=LMIQERWZRIFWNZ-UHFFFAOYSA-N

Data  5 IC50  2 Kd  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 32212   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32212(1H-indol-5-ol | cid_16054)
Affinity DataIC50:  5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32212(1H-indol-5-ol | cid_16054)
Affinity DataIC50:  8.02E+4nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA repair and recombination protein RadA(Pyrococcus furiosus)
University Of Cambridge

LigandPNGBDBM32212(1H-indol-5-ol | cid_16054)
Affinity DataKd:  2.10E+6nMAssay Description:The thermal-shift denaturation assay was performed on an iCycler iQ Real Time Detection System (BioRad) in 96-well iCycler iQ PCR plates sealed with ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM32212(1H-indol-5-ol | cid_16054)
Affinity DataEC50:  1.00E+6nMAssay Description:Activity at human alpha-7 nACh receptor expressed in Xenopus laevis oocyte assessed as increase in acetylcholine-induced currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM32212(1H-indol-5-ol | cid_16054)
Affinity DataKd:  2.10E+6nMAssay Description:Binding affinity to RAD51 (unknown origin) by isothermal calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology

Curated by ChEMBL
LigandPNGBDBM32212(1H-indol-5-ol | cid_16054)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM32212(1H-indol-5-ol | cid_16054)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM32212(1H-indol-5-ol | cid_16054)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB