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BDBM322244 (R)-N-(2,2-dimethylquinuclidin-3-yl)benzo[d]thiazole-2-carboxamide::US10183938, Compound (R)-29

SMILES: CC1(C)[C@H](NC(=O)c2nc3ccccc3s2)C2CCN1CC2

InChI Key: InChIKey=VOEWLOQZLNHFHQ-CQSZACIVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 322244   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor protein alpha-7 subunit


(Homo sapiens (Human))
BDBM322244
PNG
((R)-N-(2,2-dimethylquinuclidin-3-yl)benzo[d]thiazo...)
Show SMILES CC1(C)[C@H](NC(=O)c2nc3ccccc3s2)C2CCN1CC2
Show InChI InChI=1S/C17H21N3OS/c1-17(2)14(11-7-9-20(17)10-8-11)19-15(21)16-18-12-5-3-4-6-13(12)22-16/h3-6,11,14H,7-10H2,1-2H3,(H,19,21)/t14-/m1/s1
PDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
3.00E+3n/an/an/an/an/an/an/an/a



Axovant Sciences GmbH

US Patent


Assay Description
The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...


US Patent US10183938 (2019)


BindingDB Entry DOI: 10.7270/Q2VD71JR
More data for this
Ligand-Target Pair