BDBM322277 N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[2.2.2]octan]-3'-yl)benzo[b]thiophene-6-carboxamide::US10183938, Compound 58a
SMILES O=C(NC1C2CCN(CC2)C11CC1)c1ccc2ccsc2c1
InChI Key InChIKey=HIFHKIVBOAYGIT-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 322277
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 110nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
Affinity DataKi: 910nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair