BDBM322315 (R)-N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[2.2.2]octan]-3'-yl)thieno[2,3-b]pyridine-2-carboxamide::US10183938, Compound (R)-81

SMILES O=C(N[C@@H]1C2CCN(CC2)C11CC1)c1cc2cccnc2s1

InChI Key InChIKey=QGHXMYPQSBYWFY-CQSZACIVSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 322315   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences

US Patent
LigandPNGBDBM322315((R)-N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[2.2.2...)
Affinity DataKi:  1.50E+3nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent