BDBM322860 2-(4-(5-oxo-4-((4-(2-(piperazin-1-yl) ethoxy)phenyl)amino)-5,6- dihydropyrimido[4,5-d]pyridazin-2-yl) piperazin-1-yl)acetonitrile::US10183944, Example 230::US10647720, Ex. # 230

SMILES NC(=O)c1c(Nc2ccc(OCCN3CCNCC3)cc2)nc(nc1C=N)N1CCN(CC#N)CC1

InChI Key InChIKey=ZUDOKQORZXFTQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322860   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Asan Biosciences

US Patent
LigandPNGBDBM322860(2-(4-(5-oxo-4-((4-(2-(piperazin-1-yl) ethoxy)pheny...)
Affinity DataIC50: >100nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Asan Biosciences

US Patent
LigandPNGBDBM322860(2-(4-(5-oxo-4-((4-(2-(piperazin-1-yl) ethoxy)pheny...)
Affinity DataIC50: >100nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent