BDBM322869 2-(azepan-1-yl)-4-((4-(2-(4-(2- hydroxyethyl)piperazin-1-yl)ethoxy) phenyl)amino)pyrimido[4,5-d]pyridazin- 5(6H)-one::US10183944, Example 239::US10647720, Ex. # 239
SMILES NC(=O)c1c(Nc2ccc(OCCN3CCN(CCO)CC3)cc2)nc(nc1C=N)N1CCCCCC1
InChI Key InChIKey=PLRVOIGCBGTLTD-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 322869
Affinity DataIC50: <100nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair