BDBM32301 (1E,2E)-3-phenylacrylaldehyde (1,1-dioxido-1,2-benzisothiazol-3-yl)(2-hydroxyethyl)hydrazone::2-[(1,1-diketo-1,2-benzothiazol-3-yl)-[[(E)-3-phenylprop-2-enylidene]amino]amino]ethanol::2-[(1,1-dioxo-1,2-benzothiazol-3-yl)-[[(E)-3-phenylprop-2-enylidene]amino]amino]ethanol::2-[[1,1-bis(oxidanylidene)-1,2-benzothiazol-3-yl]-[[(E)-3-phenylprop-2-enylidene]amino]amino]ethanol::MLS000585595::SMR000207576::cid_12005471

SMILES OCCN(N=C\C=C\c1ccccc1)C1=NS(=O)(=O)c2ccccc12

InChI Key InChIKey=JYVLEFNEUSXBMY-ZCHOPRNZSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 32301   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32301((1E,2E)-3-phenylacrylaldehyde (1,1-dioxido-1,2-ben...)
Affinity DataEC50:  2.00E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32301((1E,2E)-3-phenylacrylaldehyde (1,1-dioxido-1,2-ben...)
Affinity DataEC50:  2.09E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32301((1E,2E)-3-phenylacrylaldehyde (1,1-dioxido-1,2-ben...)
Affinity DataEC50:  2.06E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 10 [11-204](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32301((1E,2E)-3-phenylacrylaldehyde (1,1-dioxido-1,2-ben...)
Affinity DataEC50:  1.17E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay