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BDBM323235 N-[(R)-1-(4-methoxybenzyl)-2-oxo-2-(3-pentyl-3-phenylazetidin-1-yl)ethyl]-3-(3-methyl-3H-imidazol-4-yl)propionamide::US9630949, 64

SMILES: CCCCCC1(CN(C1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)CCc1cncn1C)c1ccccc1

InChI Key: InChIKey=IVHKXENLVMUQSX-MUUNZHRXSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323235   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM323235
PNG
(N-[(R)-1-(4-methoxybenzyl)-2-oxo-2-(3-pentyl-3-phe...)
Show SMILES CCCCCC1(CN(C1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)CCc1cncn1C)c1ccccc1
Show InChI InChI=1S/C31H40N4O3/c1-4-5-9-18-31(25-10-7-6-8-11-25)21-35(22-31)30(37)28(19-24-12-15-27(38-3)16-13-24)33-29(36)17-14-26-20-32-23-34(26)2/h6-8,10-13,15-16,20,23,28H,4-5,9,14,17-19,21-22H2,1-3H3,(H,33,36)/t28-/m1/s1
PDB

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UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 500n/an/an/an/a



Galderma Research & Development

US Patent


Assay Description
In the presence of an activator (agonist), the melanocortin receptor will activate the cAMP pathway which, via the CRE-Luc vector, will result in the...


US Patent US9630949 (2017)


BindingDB Entry DOI: 10.7270/Q21Z46H9
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM323235
PNG
(N-[(R)-1-(4-methoxybenzyl)-2-oxo-2-(3-pentyl-3-phe...)
Show SMILES CCCCCC1(CN(C1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)CCc1cncn1C)c1ccccc1
Show InChI InChI=1S/C31H40N4O3/c1-4-5-9-18-31(25-10-7-6-8-11-25)21-35(22-31)30(37)28(19-24-12-15-27(38-3)16-13-24)33-29(36)17-14-26-20-32-23-34(26)2/h6-8,10-13,15-16,20,23,28H,4-5,9,14,17-19,21-22H2,1-3H3,(H,33,36)/t28-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.00E+3n/an/an/an/a



Galderma Research & Development

US Patent


Assay Description
In the presence of an activator (agonist), the melanocortin receptor will activate the cAMP pathway which, via the CRE-Luc vector, will result in the...


US Patent US9630949 (2017)


BindingDB Entry DOI: 10.7270/Q21Z46H9
More data for this
Ligand-Target Pair