BDBM323788 6-Bromo-N-{4-[(dimethylsulfamoyl)carbamoyl]-2-fluorophenyl}-3-methyl-2-phenylquinoline-4-carboxamide::US10189788, Example 68

SMILES CN(C)S(=O)(=O)NC(=O)c1ccc(NC(=O)c2c(C)c(nc3ccc(Br)cc23)-c2ccccc2)c(F)c1

InChI Key InChIKey=ATOXMNSTBRUFAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323788   

TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323788(6-Bromo-N-{4-[(dimethylsulfamoyl)carbamoyl]-2-fluo...)
Affinity DataIC50:  182nMAssay Description:For the characterization of test substances in respect of FP antagonism, the PGF2α-induced calcium flux in recombinant FP-expressing CHO cells w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323788(6-Bromo-N-{4-[(dimethylsulfamoyl)carbamoyl]-2-fluo...)
Affinity DataIC50:  318nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent