BDBM323865 US10189809, Compound I-137
SMILES COc1ccc(cc1)C1=Nc2nc(ncc2C(C)(C)O1)-c1cc(-c2ccon2)n(Cc2ccccc2F)n1
InChI Key InChIKey=FCOIXIHYVPQWTQ-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 323865
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Ironwood Pharmaceuticals
US Patent
Ironwood Pharmaceuticals
US Patent
Affinity DataEC50: 5.00E+4nMAssay Description:Human embryonic kidney cells (HEK293), endogenously expressing soluble guanylate cyclase (sGC), were used to evaluate the activity of test compounds....More data for this Ligand-Target Pair
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Ironwood Pharmaceuticals
US Patent
Ironwood Pharmaceuticals
US Patent
Affinity DataEC50: 5.00E+4nMAssay Description:Human embryonic kidney cells (HEK293), endogenously expressing soluble guanylate cyclase (sGC), were used to evaluate the activity of test compounds....More data for this Ligand-Target Pair