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BDBM324307 1-(tert-butyl)-N-(8-(2- ((1-methyl-1H-pyrazol- 4-yl)amino)pyrimidin- 4-yl)-2-(oxetan-3-yl)- 2,3,4,5-tetrahydro-1H- benzo[c]azepin-5-yl)- 1H-1,2,3-triazole-4- carboxamide::US10189829, Compound 71::US10227341, Compound 71::US10961237, Compound 71::US11858926, Compound 71
SMILES: Cn1cc(Nc2nccc(n2)-c2ccc3C(CCN(Cc3c2)C2COC2)NC(=O)c2cn(nn2)C(C)(C)C)cn1
InChI Key: InChIKey=JSAQBOQCZJHWMA-UHFFFAOYSA-N
Data: 4 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tyrosine-protein kinase BTK (Human) | BDBM324307![]() (1-(tert-butyl)-N-(8-(2- ((1-methyl-1H-pyrazol- 4-y...) | GoogleScholar | UniChem | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Human) | BDBM324307![]() (1-(tert-butyl)-N-(8-(2- ((1-methyl-1H-pyrazol- 4-y...) | GoogleScholar | UniChem | n/a | n/a | 505 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK (Human) | BDBM324307![]() (1-(tert-butyl)-N-(8-(2- ((1-methyl-1H-pyrazol- 4-y...) | GoogleScholar | UniChem | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosine-protein kinase BTK [14-552] (Human) | BDBM324307![]() (1-(tert-butyl)-N-(8-(2- ((1-methyl-1H-pyrazol- 4-y...) | GoogleScholar | UniChem | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||