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BDBM324307 1-(tert-butyl)-N-(8-(2- ((1-methyl-1H-pyrazol- 4-yl)amino)pyrimidin- 4-yl)-2-(oxetan-3-yl)- 2,3,4,5-tetrahydro-1H- benzo[c]azepin-5-yl)- 1H-1,2,3-triazole-4- carboxamide::US10189829, Compound 71::US10227341, Compound 71::US10961237, Compound 71::US11858926, Compound 71

SMILES: Cn1cc(Nc2nccc(n2)-c2ccc3C(CCN(Cc3c2)C2COC2)NC(=O)c2cn(nn2)C(C)(C)C)cn1

InChI Key: InChIKey=JSAQBOQCZJHWMA-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 324307   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase BTK


(Human)
BDBM324307
PNG
(1-(tert-butyl)-N-(8-(2- ((1-methyl-1H-pyrazol- 4-y...)
GoogleScholar
UniChem
n/an/a<1n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Human)
BDBM324307
PNG
(1-(tert-butyl)-N-(8-(2- ((1-methyl-1H-pyrazol- 4-y...)
GoogleScholar
UniChem
n/an/a 505n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Human)
BDBM324307
PNG
(1-(tert-butyl)-N-(8-(2- ((1-methyl-1H-pyrazol- 4-y...)
GoogleScholar
UniChem
n/an/a<1n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK [14-552]


(Human)
BDBM324307
PNG
(1-(tert-butyl)-N-(8-(2- ((1-methyl-1H-pyrazol- 4-y...)
GoogleScholar
UniChem
n/an/a<1n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair