BDBM32500 pyridine amide, 15

SMILES CC1CCN(CC1)C(=O)c1cncc(CS(=O)(=O)c2c(Cl)cccc2Cl)c1

InChI Key InChIKey=YCPLVBXZQTYYIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 32500   

Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32500(pyridine amide, 15)
Affinity DataIC50:  22nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed