BDBM325061 9-(4-(benzo[d]isoxazol-7-yl)benzyl)-2-(2-::US10189841, Compound I-267::US10399980, Compound I-267::US11161848, Compound I-267

SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3cccc4cnoc34)c2n1

InChI Key InChIKey=XBHCWRVXDMRZKM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 325061   

TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325061(9-(4-(benzo[d]isoxazol-7-yl)benzyl)-2-(2- | US1018...)
Affinity DataIC50: <200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325061(9-(4-(benzo[d]isoxazol-7-yl)benzyl)-2-(2- | US1018...)
Affinity DataIC50:  1.10E+3nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325061(9-(4-(benzo[d]isoxazol-7-yl)benzyl)-2-(2- | US1018...)
Affinity DataIC50:  1.10E+3nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent