BDBM325281 4-fluoro-N-::US10189841, Compound I-487::US10399980, Compound I-487

SMILES CC(C)NC(=O)N1CCC(F)(Cn2c3nc(ncc3[nH]c2=O)-c2ccccc2C(C)C)CC1

InChI Key InChIKey=KPGCGKWDMNLRIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325281   

TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325281(4-fluoro-N- | US10189841, Compound I-487 | US10399...)
Affinity DataIC50: >2.00E+3nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM325281(4-fluoro-N- | US10189841, Compound I-487 | US10399...)
Affinity DataIC50: <0.00200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent