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BDBM326336 (1R*,2S*)-2-(3-Aminopropyl)-1-[1-(3,3-dimethylbutyl)-1H-imidazol-4-yl]cyclopropanecarboxylic acid::US9662310, Example 1::US9662310, Example 28

SMILES: CC(C)(C)CCn1cnc(c1)[C@]1(C[C@@H]1CCCN)C(O)=O

InChI Key: InChIKey=OATNNVUVQQXLHN-BLLLJJGKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 326336   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
tafia


(Homo sapiens (Human))
BDBM326336
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(3,3-dimethylbuty...)
Show SMILES CC(C)(C)CCn1cnc(c1)[C@]1(C[C@@H]1CCCN)C(O)=O
Show InChI InChI=1S/C16H27N3O2/c1-15(2,3)6-8-19-10-13(18-11-19)16(14(20)21)9-12(16)5-4-7-17/h10-12H,4-9,17H2,1-3H3,(H,20,21)/t12-,16+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4.5n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair
tafia


(Homo sapiens (Human))
BDBM326336
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(3,3-dimethylbuty...)
Show SMILES CC(C)(C)CCn1cnc(c1)[C@]1(C[C@@H]1CCCN)C(O)=O
Show InChI InChI=1S/C16H27N3O2/c1-15(2,3)6-8-19-10-13(18-11-19)16(14(20)21)9-12(16)5-4-7-17/h10-12H,4-9,17H2,1-3H3,(H,20,21)/t12-,16+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 8.70n/an/an/an/an/an/a



DAIICHI SANKYO COMPANY, LIMITED

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)

More data for this
Ligand-Target Pair