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BDBM326355 (1R*,2S*)-2-(3-Aminopropyl)-1-[1-(2-chlorophenyl)-1H-imidazol-4-yl]cyclopropanecarboxylic acid hydrochloride::US9662310, Example 20

SMILES: CCOC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccccc1Cl

InChI Key: InChIKey=DJUGKLDQGDPBHX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326355   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM326355
PNG
((1R*,2S*)-2-(3-Aminopropyl)-1-[1-(2-chlorophenyl)-...)
Show SMILES CCOC(=O)C1(CC1CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1cn(cn1)-c1ccccc1Cl
Show InChI InChI=1S/C28H38ClN3O6/c1-8-36-23(33)28(22-17-31(18-30-22)21-14-10-9-13-20(21)29)16-19(28)12-11-15-32(24(34)37-26(2,3)4)25(35)38-27(5,6)7/h9-10,13-14,17-19H,8,11-12,15-16H2,1-7H3
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 140n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
HEPES buffered saline (20 mM HEPES, 150 mM NaCl, pH 7.4; hereinafter, referred to as HBS) was used in the preparation of a reaction solution. To 12 &...


US Patent US9662310 (2017)


BindingDB Entry DOI: 10.7270/Q2W09829
More data for this
Ligand-Target Pair