BDBM326764 US9662327, Compound 349

SMILES CC(C)[C@@H]1CN(CCN1C(=O)NCCO)c1nc(C2CC2)c2COC(C)(C)Cc2c1C=N

InChI Key InChIKey=WCLBTAYNNGACAB-FQEVSTJZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326764   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Agios Pharmaceuticals

US Patent
LigandPNGBDBM326764(US9662327, Compound 349)
Affinity DataIC50:  5.50E+3nMAssay Description:Assays were conducted in a volume of 76 μl assay buffer (150 mM NaCl, 10 mM MgCl2, 20 mM Tris pH 7.5, 0.03% bovine serum albumin) as follows in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent