BDBM326933 US9662339, 184::[(3R)-1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl]benzyl}pyrrolidin-3-yl]acetic acid

SMILES OC(=O)C[C@H]1CCN(Cc2ccc(cc2)[C@H]2COc3ccccc3O2)C1

InChI Key InChIKey=QPESCZURDNRROF-OXQOHEQNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326933   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM326933(US9662339, 184 | [(3R)-1-{4-[(2S)-2,3-dihydro-1,4-...)
Affinity DataIC50:  0.110nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent