BDBM327068 (3S)-3-{4-[(3-methoxypiperidin- 1-yl)methyl]phenyl}-2,3- dihydro[1,4]dioxino[2,3- b]pyridine::US9662339, 158

SMILES COC1CCCN(Cc2ccc(cc2)[C@H]2COc3cccnc3O2)C1

InChI Key InChIKey=NUHOYAGYYOGTKL-WHCXFUJUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327068   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327068((3S)-3-{4-[(3-methoxypiperidin- 1-yl)methyl]phenyl...)
Affinity DataIC50:  0.130nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent