BDBM327168 US9662339, 251::[(1alpha,5alpha,6alpha)-3-[(S)-4-(2,3- Dihydro-[1,4]dioxino[2,3- b]pyridin-3-yl)-benzyl]-3-aza- bicyclo[3.1.0]hexane-6-carboxylic acid (2-hydroxy-2-methyl- propyl)]-amide

SMILES CC(C)(O)CNC(=O)[C@@H]1[C@H]2CN(Cc3ccc(cc3)[C@H]3COc4cccnc4O3)C[C@@H]12

InChI Key InChIKey=RESWFBUPGRRWGR-JYRKZWEQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327168   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327168(US9662339, 251 | [(1alpha,5alpha,6alpha)-3-[(S)-4-...)
Affinity DataIC50:  0.160nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent