BDBM32764 4-(2-amino-1-hydroxy-ethyl)phenol;hydrochloride::4-(2-amino-1-hydroxyethyl)phenol;hydrochloride::4-(2-azanyl-1-oxidanyl-ethyl)phenol;hydrochloride::DL-OCTOPAMINE HYDROCHLORIDE::EN300-1723046::MLS000028414::SMR000058358::cid_102484

SMILES NCC(O)c1ccc(O)cc1

InChI Key InChIKey=QHGUCRYDKWKLMG-UHFFFAOYSA-N

Data  3 IC50  2 EC50

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 32764   

TargetCoagulation factor XI(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32764(4-(2-amino-1-hydroxy-ethyl)phenol;hydrochloride | ...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM32764(4-(2-amino-1-hydroxy-ethyl)phenol;hydrochloride | ...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at rat N-terminal FLAG-tagged TAAR1 expressed in HEK293 cells assessed as [3H]cAMP accumulation measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM32764(4-(2-amino-1-hydroxy-ethyl)phenol;hydrochloride | ...)
Affinity DataIC50:  130nMAssay Description:IC50 values were determined using 12 point 2-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM32764(4-(2-amino-1-hydroxy-ethyl)phenol;hydrochloride | ...)
Affinity DataIC50:  1.64E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyR1(Chilo suppressalis)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM32764(4-(2-amino-1-hydroxy-ethyl)phenol;hydrochloride | ...)
Affinity DataEC50:  978nMAssay Description:Agonist activity at Chilo suppressalis (rice stem borer) tyramine receptor TyR1 expressed in HEK293 cells assessed as reduction in forskolin-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed